Invitrogen™ Phospho-GluR2 (Tyr876) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106178

Product Code. 16672615

Description

Antibody detects endogenous levels of GluR2 only when phosphorylated at Tyr876.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.

Specifications

• Antigen: Phospho-GluR2 (Tyr876)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gria2
• Gene Alias: AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; GluA2; Glur2; GluR-2; GLURB; GluR-B; GluR-K2; glutamate ionotropic receptor AMPA type subunit 2; glutamate receptor; glutamate receptor 2; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA2 (alpha 2); GRIA2; HBGR2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14800, 2891, 29627
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P19491, P23819, P42262
• Gene Symbols: Gria2
• Immunogen: A synthesized peptide derived from human GRIA2(Accession P42262), corresponding to amino acid residues around phosphorylated Tyr876.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG