Invitrogen™ Phospho-GCN2 (Thr899) Recombinant Rabbit Monoclonal Antibody (JE00-51)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA556574

Product Code. 30276369

Description

Phospho-GCN2 (Thr899) Recombinant Monoclonal Antibody for Western Blot

EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.

Specifications

• Antigen: Phospho-GCN2 (Thr899)
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: D4A7V9, Q9P2K8
• Gene Symbols: EIF2AK4
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr899 of Human GCN2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: JE00-51
• Conjugate: Unconjugated
• Gene: EIF2AK4
• Gene Alias: 2610011M03; EIF2AK4; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2 alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; Gcn2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; Kiaa1338; mGCN2; PVOD2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 114859, 440275
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid