Invitrogen™ Phospho-GABRG2 (Ser327) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA14739

Product Code. 10444204

Description

This antibody is predicted to react with bovine, canine, chicken, mouse, human and non-human primates based on 100% sequence homology. In Western blot, a band at ~45 kDa is detected. Immunolabeling can be blocked by lambda-phosphatase treatment.

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: Phospho-GABRG2 (Ser327)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gabrg2
• Gene Alias: CAE2; ECA2; GABA(A) receptor subunit gamma-2; GABA(A) receptor, gamma 2; GABAA-R; GABRA2; Gabrg2; Gabrg-2; gamma2; gamma-aminobutyrate receptor type A gamma-2 subuni; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid A receptor gamma 2; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid type A receptor gamma2 subunit; gamma-aminobutyric acid type A receptor subunit gamma2; GEFSP3; LOC553402 protein; LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit gamma-2; si:ch211-145n14.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14406, 29709
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.25 mg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P18508, P22723
• Gene Symbols: Gabrg2
• Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser327 of rat GABRG2 conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG