Invitrogen™ Phospho-FER (Tyr714) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA564579

Product Code. 15732646

Description

Phospho-FER (Tyr714) Polyclonal Antibody detects endogenous levels of FER only when phosphorylated at Tyr714.

FER is a member of the FPS/FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. FER is found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes. The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines. Data suggest a biological role for Fer in regulation of leukocyte recruitment during the innate immune response.

Specifications

• Antigen: Phospho-FER (Tyr714)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FER
• Gene Alias: AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14158, 2241, 301737
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09760, P16591, P70451
• Gene Symbols: FER
• Immunogen: A synthesized peptide derived from human FER (Phospho-Tyr714).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG