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Phospho-ERF (Thr526) Polyclonal Antibody, Invitrogen™

Product Code. 15565191
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Quantity:
100 μg
Unit Size:
100µg
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15565191 100 μg 100µg
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Product Code. 15565191 Supplier Invitrogen Supplier No. PA538268

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Description

Rabbit Polyclonal Antibody

ABT1 (activator of basal transcription 1) is a nuclear protein that associates with the TATA-binding protein (TBP) and enhances basal transcription activity of class II promoters. ABT1 associates with TBP in HeLa nuclear extracts in vitro. Another protein, designated ERF, is a member of the Ets family of transcription factors. The members of the Ets family are grouped because they share a highly conserved DNA binding domain. These factors are involved in growth factor pathways and regulate both proliferation and differentiation. ERF (Ets-2 repressor factor) is a ubiquitously expressed Ets-domain protein that exhibits strong transcriptional repressor activity, suppresses Ets-induced transformation and is regulated by MAPK phosphorylation. ERF transcription may be regulated by Ets-domain proteins. Additionally, modulation of ERF activity is involved in the transcriptional regulation of genes activated during entry into G1 phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ERF (Thr526)
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ERF
Gene Accession No. P50548, P70459
Gene Alias ERF, ERF, ETS domain containing transcription factor ERF, ETS domain-containing transcription factor ERF, Ets2 repressor factor, PE 2, PE-2, PE2
Gene Symbols ERF
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human ERF around the phosphorylation site of Thr526 (P-L-TP-P-R)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13875, 2077
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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