Phospho-EpoR (Tyr368) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538483

Product Code. 15595401

Description

Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Specifications

• Antigen: Phospho-EpoR (Tyr368)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPOR
• Gene Alias: EPO R, EPO-R, epor, pEpoR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13857, 2057, 24336
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P19235, P14753, Q07303
• Gene Symbols: EPOR
• Immunogen: A synthetic phosphopeptide derived from human Epo-R around the phosphorylation site of Tyr368 (D-T-YP-L-V)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG