Invitrogen™ Phospho-EPB41 (Tyr660) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA540232

Product Code. 15536921

Description

This antibody is predicted to react with mouse based on sequence homology.

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Specifications

• Antigen: Phospho-EPB41 (Tyr660)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPB41
• Gene Alias: 4.1R; AI415518; Band 4.1; D4Ertd442e; E41P; EL1; elliptocytosis 1, RH-linked; Elp1; Elp-1; EPB4.1; EPB41; erythrocyte membrane protein band 4.1; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); erythrocyte protein band 4.1; erythrocyte skeletal protein; erythrocyte surface protein band 4.1; HE; Kiaa4056; mKIAA4056; P4.1; protein 4.1; Protein 4.1R; RGD1564762
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2035, 269587
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P11171, P48193
• Gene Symbols: EPB41
• Immunogen: Synthesized peptide derived from human 4.1R around the phosphorylation site of Y660.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG