Invitrogen™ Phospho-eIF4E (Ser209) Recombinant Rabbit Monoclonal Antibody (0I0D10)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA555315

Product Code. 30131281

Description

Phospho-eIF4E (Ser209) Recombinant Monoclonal Antibody for Western Blot, ELISA

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.

Specifications

• Antigen: Phospho-eIF4E (Ser209)
• Classification: Recombinant Monoclonal
• Concentration: 0.75 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P06730, P63074
• Gene Symbols: Eif4e
• Immunogen: A phospho specific peptide corresponding to residues surrounding S209 of human Phospho-eIF4E-S209.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 0I0D10
• Conjugate: Unconjugated
• Gene: Eif4e
• Gene Alias: AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 117045, 1977
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid