Invitrogen™ Phospho-eIF2 beta (Ser2) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA537769

Product Code. 15504711

Description

A suggested positive control for Western blot is C2C12 cells.

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Phospho-eIF2 beta (Ser2)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2S2
• Gene Alias: 2810026E11Rik; 38kDa; AA408636; AA571381; AA986487; AW822225; D2Ertd303e; EIF2; EIF2B; EIF2BA; EIF2beta; eIF-2-beta; EIF2S2; Eukaryotic translation initiation factor 2 subunit 2; eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 (beta); eukaryotic translation initiation factor 2, subunit 2 (beta, 38kDa); eukaryotic translation initiation factor 2, subunit 2 beta; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; PPP1R67; protein phosphatase 1, regulatory subunit 67
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 296302, 67204, 8894
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P20042, Q99L45
• Gene Symbols: EIF2S2
• Immunogen: Peptide sequence around phosphorylation site of serine 2 (M-S(p)-G-D-E) derived from Human eIF2-beta.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG