Invitrogen™ Phospho-DOK2 (Tyr299) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5104702

Product Code. 16611155

Description

Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyrosine 299.

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.

Specifications

• Antigen: Phospho-DOK2 (Tyr299)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DOK2
• Gene Alias: docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok2; Dok-2; DokR; Dok-R; dok-related protein; Downstream of tyrosine kinase 2; Frip; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; LOW QUALITY PROTEIN: docking protein 2; docking protein 2; p56 dok-2; p56(dok-2); p56DOK; p56dok-2
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13449, 9046
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O60496, O70469
• Gene Symbols: DOK2
• Immunogen: A synthesized peptide derived from human DOK2(Accession O60496), corresponding to amino acid residues around phosphorylated Tyr299.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG