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Phospho-Cyclin E (Thr395) Polyclonal Antibody, Invitrogen™
Description
Cyclins were first identified in invertebrates as proteins that oscillate dramatically through the cell cycle. These proteins have been well conserved through evolution and play a critical role in regulation of cell division. cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner.
Specifications
Specifications
| Antigen | Phospho-Cyclin E (Thr395) |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | CCNE1 |
| Gene Accession No. | P24864 |
| Gene Alias | CCNE, CCNE1, G1/S-specific cyclin E1, E-S |
| Gene Symbols | CCNE1 |
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