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Invitrogen™ Phospho-Crk (Tyr221) Polyclonal Antibody
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Product Code. 11576990
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Quantity:
100 μL
Unit Size:
100µL
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11576990 100 μL 100µL
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Product Code. 11576990 Supplier Invitrogen™ Supplier No. PA517747

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Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other tyrosine-phosphorylated proteins.

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Crk (Tyr221)
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Crk
Gene Accession No. P46108, Q16539
Gene Alias Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; CRK; CRK proto-oncogene, adaptor protein; CRK1; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; CSBP2; CSPB1; CT-10 related kinase 3; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; I79_016605; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38a; p38ALPHA; p38-alpha; p38alpha Exip; p38Hog; p38MAPK; PRKM14; PRKM15; Proto-oncogene c-Crk; reactive kinase; RK; SAPK2A; stress-activated protein kinase 2A; tRNA synthetase cofactor p38; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian); v-crk sarcoma virus CT10 oncogene-like protein
Gene Symbols Crk, Mapk14
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pTyr221 of human CrkII.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100689104, 100762827, 1398, 1432
Target Species Human, Hamster
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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