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Invitrogen™ Phospho-CENPA (Ser7) Polyclonal Antibody

Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other histone proteins, including Histone H3.
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Specifications
Specifications
| Antigen | Phospho-CENPA (Ser7) |
| Applications | Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 26 μg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 |
| Gene | Cenpa |
| Gene Accession No. | P49450 |
| Gene Alias | CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607 |
| Gene Symbols | Cenpa |
| Show More |
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