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Phospho-C5AR1 (Ser327) Polyclonal Antibody, Invitrogen™

Product Code. 15722886
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Quantity:
100 μL
Unit Size:
100µL
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15722886 100 μL 100µL
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Product Code. 15722886 Supplier Invitrogen Supplier No. PA564820

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Description

Rabbit Polyclonal Antibody

Phospho-C5AR1 (Ser327) Polyclonal Antibody detects endogenous levels of C5AR1 only when phosphorylated at Ser327.

C5AR1 is an C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. C5AR1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, C5AR1 stimulates chemotaxis, granule enzyme release and superoxide anion production. C5a is likely a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with C5AR1 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-C5AR1 (Ser327)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene C5AR1
Gene Accession No. P21730
Gene Alias C5AR, C5R1
Gene Symbols C5AR1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CD88 (Phospho-Ser327)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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