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Invitrogen™ Phospho-c-Jun (Ser63) Polyclonal Antibody
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Product Code. 11597130
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Quantity:
100 μL
Unit Size:
100µL
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11597130 100 μL 100µL
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Product Code. 11597130 Supplier Invitrogen™ Supplier No. PA517890

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Description

Rabbit Polyclonal Antibody

Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit. This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays. It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications. Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay. It is not recommended to aliquot this antibody. This antibody does not recognize the phosphorylated forms of JunD or JunB.

c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
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Specifications

Antigen Phospho-c-Jun (Ser63)
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 153 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene JUN
Gene Accession No. P05412, P05627, P17325, P56432
Gene Alias Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Gene Symbols JUN
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues around pSer63 of human c-Jun.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16476, 24516, 3725, 396913
Target Species Human, Mouse, Rat, Monkey, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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