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Invitrogen™ Phospho-C-Jun/D-Jun (Ser73, Ser100) Recombinant Rabbit Monoclonal Antibody (K01_2K98)

Product Code. 30825828
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30825828 50 μL
30825603 100 μL
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Product Code. 30825828 Supplier Invitrogen™ Supplier No. MA565436

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Rabbit Recombinant Monoclonal Antibody

Phospho-C-Jun/D-Jun (Ser73, Ser100) Recombinant Monoclonal Antibody for Western Blot

C-Jun/D-Jun are members of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016].
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Specifications

Antigen Phospho-C-Jun/D-Jun (Ser73, Ser100)
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2K98
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene Jund
Gene Accession No. P05412, P05627, P15066, P17325, P17535, P52909
Gene Alias Activator Protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; CJUN; C-JUN; c-Jun protein; enhancer-binding protein AP1; fj36h07; immediate early; JUN; Jun A; Jun activation domain binding protein; jun D proto-oncogene; jun oncogene; jun proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; p39; Proto-Oncogene CJun; proto-oncogene c-Jun; Rjg-9; si:dkey-251j8.3; transcription factor; transcription factor AP-1; Transcription Factor AP-1 Subunit Jun; Transcription Factor Jun; Transcription factor jun-D; Unknown (protein for MGC:65863); V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog; wu:fj36h07; zgc:65863
Gene Symbols JUN, Jund
Host Species Rabbit
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser73 of human Jun.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16476, 16478, 24516, 24518, 3725, 3727
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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