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Invitrogen™ Phospho-C-Jun/D-Jun (Ser73, Ser100) Recombinant Rabbit Monoclonal Antibody (K01_2K98)
Description
Phospho-C-Jun/D-Jun (Ser73, Ser100) Recombinant Monoclonal Antibody for Western Blot
C-Jun/D-Jun are members of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016].
Specifications
Specifications
| Antigen | Phospho-C-Jun/D-Jun (Ser73, Ser100) |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2K98 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4 |
| Gene | Jund |
| Gene Accession No. | P05412, P05627, P15066, P17325, P17535, P52909 |
| Gene Alias | Activator Protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; CJUN; C-JUN; c-Jun protein; enhancer-binding protein AP1; fj36h07; immediate early; JUN; Jun A; Jun activation domain binding protein; jun D proto-oncogene; jun oncogene; jun proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; p39; Proto-Oncogene CJun; proto-oncogene c-Jun; Rjg-9; si:dkey-251j8.3; transcription factor; transcription factor AP-1; Transcription Factor AP-1 Subunit Jun; Transcription Factor Jun; Transcription factor jun-D; Unknown (protein for MGC:65863); V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog; wu:fj36h07; zgc:65863 |
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