Invitrogen™ Phospho-C-Jun/D-Jun (Ser73, Ser100) Recombinant Rabbit Monoclonal Antibody (23GB4495), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA552705

Product Code. 30088519

Description

C-Jun/D-Jun are members of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016].

Specifications

• Antigen: Phospho-C-Jun/D-Jun (Ser73, Ser100)
• Classification: Recombinant Monoclonal
• Concentration: 3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P05412, P05627, P15066, P17325, P17535, P52909
• Gene Symbols: JUN, Jund
• Immunogen: A synthesized peptide derived from human Phospho-c-Jun (Ser73)+JunD (Ser100) (66-80AA).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 23GB4495
• Conjugate: Unconjugated
• Gene: JUN
• Gene Alias: Activator Protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; CJUN; C-JUN; c-Jun protein; enhancer-binding protein AP1; fj36h07; immediate early; JUN; Jun A; Jun activation domain binding protein; jun D proto-oncogene; jun oncogene; jun proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; p39; Proto-Oncogene CJun; proto-oncogene c-Jun; Rjg-9; si:dkey-251j8.3; transcription factor; transcription factor AP-1; Transcription Factor AP-1 Subunit Jun; Transcription Factor Jun; Transcription factor jun-D; Unknown (protein for MGC:65863); V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog; wu:fj36h07; zgc:65863
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16476, 16478, 24516, 24518, 3725, 3727
• Content And Storage: -20°C
• Form: Liquid