Invitrogen™ Phospho-C/EBP epsilon (Ser181) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105657

Product Code. 16604515

Description

Antibody detects endogenous levels of C/EBP epsilon only when phosphorylated at ser181.

C/EBP alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP alpha appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP alpha.

Specifications

• Antigen: Phospho-C/EBP epsilon (Ser181)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CEBPE
• Gene Alias: C EBP; c/EBP epsilon; C/EBPe; C/EBPepsilon; C/EBP-epsilon; C/EBP-related protein 1; C/EPBe; CCAAT/enhancer binding protein (C/EBP), epsilon; CCAAT/enhancer binding protein , epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; Crp1; Gm294
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1053, 110794, 25410
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P56261, Q15744, Q6PZD9
• Gene Symbols: CEBPE
• Immunogen: A synthesized peptide derived from human CEBPE(Accession Q15744), corresponding to amino acid residues around phosphorylated Ser181.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG