Invitrogen™ Phospho-BAD (Ser112) Recombinant Rabbit Monoclonal Antibody (BADS112-B9), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA537060

Product Code. 17166648

Beskrivning

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Specifikationer

• Antigen: Phospho-BAD (Ser112)
• Classification: Recombinant Monoclonal
• Conjugate: APC
• Gene: BAD
• Gene Alias: AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
• Host Species: Rabbit
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 12015, 572, 64639
• Content And Storage: 4°C
• Form: Liquid

• Applications: Flow Cytometry
• Clone: BADS112-B9
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Accession No.: O35147, Q61337, Q92934
• Gene Symbols: BAD
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG λ