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Phospho-Aurora A (Ser342) Polyclonal Antibody, Invitrogen™

Product Code. 15585641
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Quantity:
100 μg
Unit Size:
100µg
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15585641 100 μg 100µg
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Product Code. 15585641 Supplier Invitrogen Supplier No. PA538730

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Description

Rabbit Polyclonal Antibody

Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Aurora A (Ser342)
Applications Peptide ELISA
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene AURKA
Gene Accession No. O14965, P97477, P59241
Gene Alias AIK, ARK1, AYK1, Aurora-A, Aurora-family kinase 1, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, BTAK, Breast-tumor-amplified kinase, EC 2.7.11.1, IAK1, Ipl1- and aurora-related kinase 1, STK15, STK6, Serine/threonine kinase 15, Serine/threonine
Gene Symbols AURKA
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human AurA around the phosphorylation site of Ser342 (R-I-SP-R-V)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20878, 261730, 6790
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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