Invitrogen™ Phospho-AS160 (Ser570) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105405

Product Code. 16601855

Description

Antibody detects endogenous levels of AS160 only when phosphorylated at Ser570.

AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).

Specifications

• Antigen: Phospho-AS160 (Ser570)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBC1D4
• Gene Alias: 5930406J04Rik; A930035N22; Akt substrate of 160 kDa; AS160; AV295684; DKFZp779C0666; Kiaa0603; NIDDM5; OTTHUMP00000040818; RGD1561609; RP11-159J2.1; RP11-159J2.3; similar to TBC1 domain family member 4; TBC (Tre-2, BUB2, CDC16) domain-containing protein; TBC Tre-2; TBC1 domain family member 4; TBC1 domain family, member 4; TBC1D4
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 210789, 306117, 9882
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O60343, Q8BYJ6
• Gene Symbols: TBC1D4
• Immunogen: A synthesized peptide derived from human TBC1D4(Accession O60343), corresponding to amino acid residues around phosphorylated Ser570.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG