Invitrogen™ Phospho-ARHGAP42 (Tyr376) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105369

Product Code. 16641815

Description

Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr376.

This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.

Specifications

• Antigen: Phospho-ARHGAP42 (Tyr376)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGAP42
• Gene Alias: 9030420J04Rik; Arhgap42; BE136619; Graf3; RGD1564081; Rho GTPase activating protein 42; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; rho-type GTPase-activating protein 42; TMEM133; VRho GTPase activating protein 42
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 143872, 71544
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: A6NI28, B2RQE8
• Gene Symbols: ARHGAP42
• Immunogen: A synthesized peptide derived from human ARHGAP42(Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr376.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG