Phospho-alpha Catenin (Ser641) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538750

Product Code. 15585661

Description

Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.

Specifications

• Antigen: Phospho-alpha Catenin (Ser641)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTNNA1
• Gene Alias: Catenin alpha-1, Alpha E-catenin, Cadherin-associated protein, Renal carcinoma antigen NY-REN-13, CTNNA1, Catenin-alpha1, Catenin alpha1, alphaE-catenin, Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein, CTNNA2, CAPR, Catenin-alpha2, Catenin alpha2, alphaN-catenin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12385, 1495, 307505
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P35221, P26231
• Gene Symbols: CTNNA1
• Immunogen: A synthetic phosphopeptide derived from human Catenin-alpha1 around the phosphorylation site of Ser641 (D-D-SP-D-F)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG