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Invitrogen™ Phospho-alpha Adducin (Thr445) Polyclonal Antibody
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Product Code. 15584021
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Quantity:
100 μL
Unit Size:
100µL
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15584021 100 μL 100µL
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Product Code. 15584021 Supplier Invitrogen™ Supplier No. PA536731

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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 81 kDa. Purity is >95% by SDS-PAGE.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-alpha Adducin (Thr445)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ADD1
Gene Accession No. P35611, Q63028, Q9QYC0
Gene Alias Add1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; erythrocyte adducin subunit alpha
Gene Symbols ADD1
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human Adducin alpha around the phosphorylation site of Threonine 445.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11518, 118, 24170
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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