PHLDA2 Polyclonal Antibody, Invitrogen™

Goat Polyclonal Antibody

Brand:  Invitrogen PA5142083

Product Code. 17837292

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000. Preliminary analysis showed no signal in Western Blot.

TSSC3 (Tumor-suppressing STF cDNA 3 protein), also known as PHLDA2 (pleckstrin homology-like domain family A member 2), BWR1C, HLDA2 or IPL, is a cytoplasmic protein that is involved in fetal and placental growth. Expressed at high levels in placenta and adult prostate and at low levels in liver, lung and brain, TSSC3 is an apoptosis-related protein that acts as a negative growth regulator and is expressed during normal human development. TSSC3, a protein expressed from the maternal allele, is imprinted on placenta, liver and fetal tissues during embryogenesis and is removed once development is complete. Defects or alterations in the gene encoding TSSC3 are associated with several afflictions such as lung, ovarian and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms tumor, low birth weight and adrenocortical carcinoma.

Specifications

• Antigen: PHLDA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHLDA2
• Gene Alias: Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein; BRW 1C; BRW1C; BWR 1C; BWR1C; HLDA 2; HLDA2; Imprinted in placenta and liver protein; IPL; p17-Beckwith-Wiedemann region 1 C; p17-Beckwith-Wiedemann region 1C; p17-BWR1C; PHLDA2; pleckstrin homology like domain family A member 2; pleckstrin homology-like domain family A member 2; pleckstrin homology-like domain, family A, member 2; Pphlda2; protein 50C15; TSSC 3; TSSC3; tumor suppressing subchromosomal transferable fragment cDNA 3; tumor suppressing subtransferable candidate 3; Tumor-suppressing STF cDNA 3 protein; tumor-suppressing subchromosomal transferable fragment 3; tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein; tumor-supressing STF cDNA 3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 7262
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q53GA4
• Gene Symbols: PHLDA2
• Immunogen: Peptide with sequence C-EPSRPSPQPKPRTP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid