Invitrogen™ PHGDH Monoclonal Antibody (01)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA529479

Product Code. 16313534

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human PGDH/PHGDH.

PHGDH gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Specifications

• Antigen: PHGDH
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O43175
• Gene Symbols: PHGDH
• Immunogen: Recombinant Human PGDH/PHGDH protein (Met1-Phe533).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: 01
• Conjugate: Unconjugated
• Gene: PHGDH
• Gene Alias: 2-oxoglutarate reductase; 3PGDH; 3-PGDH; 3-phosphoglycerate dehydrogenase; 3-phosphoglycerate dehyrogenase; 4930479N23; A10; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; HEL-S-113; Malate dehydrogenase; NLS; NLS1; PDG; PGAD; PGD; PGDH; PGDH3; Phgdh; PHGDHD; phosphoglycerate dehydrogenase; SERA
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 26227
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid