Invitrogen™ PHF7 Monoclonal Antibody (1E9)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA521951

Product Code. 15589052

Description

Peptide Sequence: GRDSFEDEGR WCLILCATCG SHGTHRDCSS LRSNSKKWEC EECSPAAATD YIPENSGDIP CCSSTFHPEE HFCRDNTLEE NPGLSWTDWP EPSLLEKPES.

Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.

Specifications

• Antigen: PHF7
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9BWX1
• Gene Symbols: PHF7
• Immunogen: PHF7 (NP_057567.3, 258 a.a. ~ 357 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 1E9
• Conjugate: Unconjugated
• Gene: PHF7
• Gene Alias: 1700006H01Rik; 1700010P14Rik; AI427892; AW555949; HSPC045; HSPC226; NYD-SP6; PHD finger protein 7; PHF7; testicular secretory protein Li 34; testis development protein NYD-SP6
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51533
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid