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Invitrogen™ PHF12 Recombinant Mouse Monoclonal Antibody (K8U017_20C4)
Description
Immunogen sequence: RSASKTELKA IAHARILERR ASRPGTPTSS ASTETPTSEQ NDVDEDIIDV DEEPVAAEPD YVQPQLRRPF ELLIAAAMER NPTQFQLPNE LTCTTALPGS SKRRRKEETT GKNVKKTQHE LDHNGLVPLP Highest antigen sequence identity to the following orthologs: Mouse - 97%, Pig - 99%, Cynomolgus monkey - 99%.
Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional TLE5 complexes to DNA. [UniProt].
Specifications
Specifications
| Antigen | PHF12 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Recombinant Monoclonal |
| Clone | K8U017_20C4 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| Gene | PHF12 |
| Gene Accession No. | Q96QT6 |
| Gene Alias | 2410142K10Rik; F630045O13; KIAA1523; mKIAA1523; Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; phf12; PHF12 (HGNC:20816) |
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