Phenyl chlorothionoformate, 98+%

Product Code.	Quantity	unitSize
11374314	1 g	1g
11384314	5 g	5g
11394314	25 g	25g

Product Code. 11374314 Supplier Thermo Scientific Alfa Aesar Supplier No. L00838.03

Beschreibung

CAS: 1005-56-7 | C7H5ClOS | 172.63 g/mol

Phenyl chlorothionoformate has been used in stereo directed synthesis of optically active, (-)-mintlactone, synthesis of peptide α-thioesters having a variety of C-terminal amino acids, synthesis of scyllo-inositol derivatives, thionocarbonylation of unprotected thymine nucleosides, preparation of phenoxythiocarbonyl esters of protected ribonucleosides. It is also used as a reagent in the thionocarbonylation of unprotected thymine nucleosides. It forms phenoxythiocarbonyl esters of protected ribonucleosides which can be reduced by tributyltin hydride to deoxyribonucleosides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenyl chlorothionoformate has been used in stereo directed synthesis of optically active, (-)-mintlactone, synthesis of peptide α-thioesters having a variety of C-terminal amino acids, synthesis of scyllo-inositol derivatives, thionocarbonylation of unprotected thymine nucleosides, preparation of phenoxythiocarbonyl esters of protected ribonucleosides. It is also used as a reagent in the thionocarbonylation of unprotected thymine nucleosides. It forms phenoxythiocarbonyl esters of protected ribonucleosides which can be reduced by tributyltin hydride to deoxyribonucleosides.

Solubility
Soluble in water.

Notes
Moisture, Heat Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.

Spezifikation

Chemische Identifikatoren

• CAS: 1005-56-7
• Molecular Formula: C7H5ClOS
• Molecular Weight (g/mol): 172.63
• MDL Number: MFCD00004920
• InChI Key: KOSYAAIZOGNATQ-UHFFFAOYSA-N
• Synonym: o-phenyl carbonochloridothioate, phenyl chlorothionoformate, o-phenyl chlorothioformate, phenyl chlorothioformate, phenyl thioxochloroformate, phenyl chlorothionocarbonate, phenoxythiocarbonyl chloride, chlorothioformic acid phenyl ester, o-phenyl chlorothionoformate, o-phenyl chlorothiocarbonate
• PubChem CID: 70498
• SMILES: ClC(=S)OC1=CC=CC=C1

• Density: 1.248
• Boiling Point: 81°C to 83°C (6 mmHg)
• Flash Point: 81°C (177°F)
• Odor: Acrid
• Refractive Index: 1.5804
• Quantity: 1 g
• UN Number: UN3265
• Beilstein: 774830
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in water.
• IUPAC Name: phenyl chloromethanethioate
• Formula Weight: 172.63
• Percent Purity: ≥98%
• Chemical Name or Material: Phenyl chlorothionoformate

Sicherheit und Handhabung

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only