Phenyl chloroformate, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11444040	Thermo Scientific Alfa Aesar A12618.22	100 g
11450443	Thermo Scientific Alfa Aesar A12618.30	250 g
11458680	Thermo Scientific Alfa Aesar A12618.36	500 g
11440443	Thermo Scientific Alfa Aesar A12618.0B	1000 g

Description

Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

Solubility
Miscible with N,N-dimethylformamide.

Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, alcohols and amines. Hydrolyses in water.

Chemical Identifiers

• CAS: 1885-14-9
• Molecular Weight (g/mol): 156.57
• InChI Key: AHWALFGBDFAJAI-UHFFFAOYSA-N
• PubChem CID: 15891
• SMILES: ClC(=O)OC1=CC=CC=C1

• Molecular Formula: C7H5ClO2
• MDL Number: MFCD00000637
• Synonym: phenyl chloroformate, chloroformic acid phenyl ester, phenyl chlorocarbonate, carbonochloridic acid, phenyl ester, phenoxycarbonyl chloride, formic acid, chloro-, phenyl ester, fenylester kyseliny chlormravenci, phenylchloroformate, unii-6tnd0d6d3y, 6tnd0d6d3y
• IUPAC Name: phenyl carbonochloridate

Specifications

• CAS: 1885-14-9
• Density: 1.246
• Flash Point: 76°C (169°F)
• Refractive Index: 1.511
• UN Number: UN2746
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with N,N-dimethylformamide.
• SMILES: ClC(=O)OC1=CC=CC=C1
• Molecular Weight (g/mol): 156.57
• Formula Weight: 156.57
• Chemical Name or Material: Phenyl chloroformate

• Melting Point: -38°C
• Boiling Point: 188°C to 189°C
• Molecular Formula: C7H5ClO2
• MDL Number: MFCD00000637
• Beilstein: 606778
• Synonym: phenyl chloroformate, chloroformic acid phenyl ester, phenyl chlorocarbonate, carbonochloridic acid, phenyl ester, phenoxycarbonyl chloride, formic acid, chloro-, phenyl ester, fenylester kyseliny chlormravenci, phenylchloroformate, unii-6tnd0d6d3y, 6tnd0d6d3y
• InChI Key: AHWALFGBDFAJAI-UHFFFAOYSA-N
• IUPAC Name: phenyl carbonochloridate
• PubChem CID: 15891
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H330-H314-H318-H227-H302-H317
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Harmful if swallowed.
May cause an allergic skin reaction.

P210-P235-P260-P264b-P270-P271-P272-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c

H227-H302-H314-H317-H330-H335

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: PHENYL CHLOROFORMATE

missing translation for 'einecsNumber' : 217-547-8

missing translation for 'rtecsNumber' : FG3850000

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold; Store under Nitrogen

RUO – Research Use Only