Invitrogen™ PHAP I Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596418

Product Code. 16599251

Description

Immunogen sequence: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE; Positive Samples: 293T, HepG2, HL-60, MCF7, Raji, U-251MG, Mouse brain, HT-29; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus.

PHAP I is implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Specifications

• Antigen: PHAP I
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANP32A
• Gene Alias: Acid nuclear phosphoprotein 32 (leucine rich); acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32; acidic nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein 32 family, member A; acidic nuclear phosphoprotein pp32; Anp32; ANP32A; C15orf1; cerebellar leucine rich acidic nuclear protein; hepatopoietin Cn; HPPCn; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANP; Leucine-rich acidic nuclear protein; leucine-rich acidic nuclear protein LANP; MAPM; Mapmodulin; MGC119787; MGC150373; PHAP1; PHAPI; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; pp32; Putative HLA-DR-associated protein I; putative human HLA class II associated protein I; vacidic (leucine-rich) nuclear phosphoprotein 32 family, member A; W91701
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11737, 25379, 8125
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O35381, P39687, P49911
• Gene Symbols: ANP32A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_0062961).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG