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Tocris Bioscience™ PF 3644022

Product Code. 18085092
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10 mg
Unit Size:
10mg
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Product Code. 18085092 Supplier Tocris Bioscience™ Supplier No. 4279/10

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266.90 GBP valid until 2026-03-31
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Description

Potent MK2 inhibitor

Potent, ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) (IC50 = 5.2 nM; Ki = 3 nM). Inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM); exhibits oral efficacy in acute and chronic inflammatory models.
TRUSTED_SUSTAINABILITY

Specifications

CAS 1276121-88-0
Quantity 10 mg
Molecular Formula C21H18N4OS
Formula Weight 374.46
Purity >98%
Molecular Weight (g/mol) 374.462
Chemical Name or Material PF 3644022
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