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Tocris Bioscience™ PF 3644022

Description
Potent, ATP-competitive inhibitor of mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) (IC50 = 5.2 nM; Ki = 3 nM). Inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM); exhibits oral efficacy in acute and chronic inflammatory models.
Specifications
Specifications
| CAS | 1276121-88-0 |
| Quantity | 10 mg |
| Molecular Formula | C21H18N4OS |
| Formula Weight | 374.46 |
| Purity | >98% |
| Molecular Weight (g/mol) | 374.462 |
| Chemical Name or Material | PF 3644022 |
Product Title
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