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  5. Tocris Bioscience™ PF 3084014 hydrobromide

Tocris Bioscience™ PF 3084014 hydrobromide
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Product Code. p-7110895
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18758688

Brand: Tocris Bioscience™ 5751/10

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Description

Potent γ-secretase inhibitor

PF 3084014 hydrobromide is a potent γ-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively). Reduces Aβ in brain, CSF and plasma in mice and guinea pigs.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (2 S)-2-[[(2 S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1 H-imidazol-4-yl]pentanamide dihydrobromide
CAS 1962925-29-6
Quantity 10 mg
Target gamma-Secretase
Molecular Formula C27H41F2N5O.HBr
Formula Weight 651.47
Purity 98%
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