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Tocris Bioscience™ PF 04671536 hydrochloride

Product Code. 18777108
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5 mg
25 mg
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18777108 25 mg 25mg
18766378 5 mg 5mg
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Product Code. 18777108 Supplier Tocris Bioscience™ Supplier No. 6024/25

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Potent and selective PDE8B/8A inhibitor

PF 04671536 hydrochloride is a potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
CAS 1305116-67-9
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C14H18N8OS.HCl
Formula Weight Observed MW: 382.87
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