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Tocris Bioscience™ PF 04671536 hydrochloride
Description
PF 04671536 hydrochloride is a potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
Specifications
Specifications
| Chemical Name or Material | 5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride |
| CAS | 1305116-67-9 |
| Assay Percent Range | >98% |
| Quantity | 25 mg |
| Molecular Formula | C14H18N8OS.HCl |
| Formula Weight | Observed MW: 382.87 |
Product Title
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