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Tocris Bioscience™ PF 04418948
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Product Code. 30001577
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001577

Brand: Tocris Bioscience™ 4818/10

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This item is not returnable. View return policy

Description

Potent and selective EP2 receptor antagonist

Potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1078166-57-0
Molecular Formula C23H20FNO5

Specifications

Quantity 10 mg
Formula Weight 409.41
Purity 98%
Molecular Weight (g/mol) 409.413
Chemical Name or Material PF 04418948
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