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Pexmetinib, MedChemExpress

Product Code. p-200099628
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Product Code. 16497176

Brand: Medchem Express HY16782

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Description

MedChemExpress Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia.

Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia.

Specifications

Chemical Name or Material Pexmetinib
CAS 945614-12-0
Color Off-White
Purity Grade Notes Research
Molecular Formula C31H33FN6O3
Quantity 100 mg
Synonym ARRY-614
Solubility Information DMSO : ≥ 125 mg/mL (224.57 mM)
SMILES O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5
Molecular Weight (g/mol) 556.63
Formula Weight 556.63
Percent Purity 98.3%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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