Invitrogen™ PEX13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113259

Product Code. 17101124

Description

PEX13 Polyclonal Antibody for Western Blot, IHC (P), ELISA

PEX13 (Peroxisomal Biogenesis Factor 13) is a gene located on chromosome 2p15 that encodes a peroxisomal membrane protein essential for the biogenesis and function of peroxisomes, which are cellular organelles involved in lipid metabolism and detoxification of reactive oxygen species. PEX13 is a component of the peroxisomal import machinery that specifically recognizes and binds to peroxisomal targeting signal 1 (PTS1) containing proteins, facilitating their import into the peroxisome matrix. Mutations in the PEX13 gene can lead to Zellweger spectrum disorders, a group of peroxisome biogenesis disorders (PBDs) characterized by defects in multiple peroxisomal metabolic pathways, leading to severe developmental issues, neurological deficits, and often early lethality. Studies of PEX13 have helped elucidate the mechanisms of peroxisomal protein import and the broader implications of peroxisomal dysfunction in human disease.

Specifications

• Antigen: PEX13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEX13
• Gene Alias: NALD; PBD11A; PBD11B; Peroxin-13; peroxisomal biogenesis factor 13; peroxisomal membrane protein PEX13; peroxisome biogenesis factor 13; Pex13; ZWS
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 305581, 5194
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 3.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q92968
• Gene Symbols: PEX13
• Immunogen: Recombinant Human Peroxisomal membrane protein PEX13 protein (1-130AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG