Invitrogen™ PERP Recombinant Rabbit Monoclonal Antibody (24GB1630)

Rabbit Recombinant Monoclonal Antibody

Codice del prodotto	Marca	Quantity
30276572	Invitrogen™ MA557568	100 μL
30276108	Invitrogen™ MA557569	20 μL

Descrizione

PERP Recombinant Monoclonal Antibody for Western Blot, Flow

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.

Specifica

• Antigen: PERP
• Concentration: 1.2 mg/mL
• Applications: Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q96FX8
• Gene ID (Entrez): 64065
• Immunogen: A synthesized peptide derived from human PERP (aa 165-193).
• Product Type: Antibody

• Clone: 24GB1630
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: PERP
• Gene Alias: 1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW
• Gene Symbols: PERP
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography