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Invitrogen™ PERP Polyclonal Antibody

Product Code. 12848192
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12848192 100 μg 100µg
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Product Code. 12848192 Supplier Invitrogen™ Supplier No. PA519980

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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~21kDa. A suggested positive control is A431 cell lysate. PA5-19980 can be used with blocking peptide PEP-0104.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PERP
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PERP
Gene Accession No. Q96FX8
Gene Alias 1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW
Gene Symbols PERP
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64065
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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