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Perlecan Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5140142

Additional Details : Weight : 0.01000kg

Product Code. 17834660

  • £353.00 / 100µL
Estimated Shipment: 20-08-2024
to see stock.

Description

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: RGMVFGIPDG VLELVPQRGP CPDGHFYLEH SAACLPCFCF GITSVCQSTR RFRDQIRLRF DQPDDFKGVN VTMPAQPGTP PLSSTQLQID PSL

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Specifications

Specifications

Perlecan
Polyclonal
Unconjugated
HSPG2
AI852380; Basement membrane-specific heparan sulfate proteoglycan core protein; Endorepellin; endorepellin (domain V region); heparan sulfate proteoglycan 2; HSPG; Hspg2; LG3 peptide; LOC313641; Pcn; per; perlecan; perlecan (heparan sulfate proteoglycan 2); perlecan proteoglycan; PLC; PRCAN; RP11-132G19.2; SJA; SJS; SJS1
Rabbit
Antigen affinity chromatography
RUO
3339
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry
0.2 μg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P98160
HSPG2
Recombinant protein corresponding to Human HSPG2
100 μL
Primary
Human
Antibody
IgG
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