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  5. Tocris Bioscience™ Perifosine

Tocris Bioscience™ Perifosine
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Product Code. p-7121038
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18723168

Brand: Tocris Bioscience™ 6087/10

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Description

PKB/Akt inhibitor; also modulates Kv2.1 current

Perifosine is a PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling. Also inhibits MAPK pathway and induces autophagy. Induces apoptosis in leukemia cell lines. Decreases Kv2.1 current amplitude by modulating its inactivation gating. Antitumor. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material Perifosine
CAS 157716-52-4
Synonym Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Quantity 10 mg
Solubility Soluble to 100mM in water and to 100mM in ethanol
Molecular Formula C25H52NO4P
Formula Weight 461.66
Physical Form Solid
Color White
Product Type Bioactive Small Molecule
Purity >98%
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For Research Use Only.

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