Invitrogen™ PER3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA540922

Artikelnummer. 15544492

Beschreibung

Peptide sequence: DATLFCEPWT LNMQPAPLTS EEFKHVGLTA AVLSAHTQKE EQNYVDKFRE Sequence homology: Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 86%; Rat: 93%; Sheep: 86%; Zebrafish: 79%.

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Spezifikation

• Antigen: PER3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PER3
• Gene Alias: 2810049O06Rik; Cell growth-inhibiting gene 13 protein; circadian clock protein PERIOD 3; FASPS3; GIG13; hPER3; mPER3; Per3; period circadian clock 3; period circadian protein 3; period circadian protein homolog 3; period homolog 3; period3; rper3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8863
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P56645
• Gene Symbols: PER3
• Immunogen: Synthetic peptide directed towards the C-terminal of human PER3 (aa 647-696).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG