Gibco™ PeproGMP™ Human IL-7 Recombinant Protein, PeproTech®

Product Code. 30275505

Brand: Gibco™ GMP2000750UG

Beskrivning

Recombinant Protein

PeproTech Recombinant Human IL-7 is a 17.4 kDa protein containing 152 amino acid residues. PeproGMP IL-7 can be used with PeproGMP IL-15 in CTS NK-Xpander medium for natural killer (NK) cell differentiation from pluripotent stem cells. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the Certificate of Analysis. All PeproGMP™ products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter 1043 Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.

Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.

Specifikationer

• Accession Number: P13232, P16871
• For Use With (Application): Control, Western Blot Control, Bioactivity
• Format: Lyophilized
• Formulation: Protein with no preservative
• Gene ID (Entrez): 3574, 3575
• Molecular Weight (g/mol): 17.4 kDa
• Name: PeproGMP™ Human IL-7
• Purification Method: Purified
• Quantity: 50 μg
• Storage Requirements: -20°C or -80°C if preferred
• Regulatory Status: GMP
• Endotoxin Concentration: ≤0.1 EU/μg
• Gene Alias: A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7
• Common Name: IL-7
• Gene Symbol: Il7, IL7r
• Biological Activity: Determined by the proliferation of mouse 2E8 cells. PeproGMP Recombinant Human IL-7 ha been tested against the WHO standard NIBSC 90/530.
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EH
• Content And Storage: -20°Cor to +80°C if preferred
• Activity: Determined by the proliferation of mouse 2E8 cells. PeproGMP Recombinant Human IL-7 has been tested against the WHO standard NIBSC 90/530. Find the International Unit (IU) value <a href='https://www.thermofisher.com/us/en/home/life-science/cell-culture/cell-culture-learning-center/recombinant-protein-information/international-units.html'>here</a>.
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.