Invitrogen™ PEO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551715

Product Code. 15749670

Description

Immunogen sequence: SKAPEFEDSE EVRRIWNRAI PLWELPDQEE VQLADTMFGL TKVTDDTLKR FSVRYLRPAR SLVFPWFSPG GSGLRGLKLL EAKCQGDGVS YEETTIPRPS AYHNLFGLPL ISRRDAEVVL TSRELDSLAL NQSTG Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 78%.

Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: PEO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TWNK
• Gene Alias: ataxin 8; Ataxin8; ATXN 8; ATXN8; C10 orf2; C10orf 2; C10orf2; C18H10orf2; C1H10orf2; C26H10orf2; C28H10orf2; chromosome 10 open reading frame 2; D19Ertd626e; fi04d09; FLJ21832; IOSCA; mitochondrial twinkle protein; MTDPS7; PEO; PEO 1; peo1; PEOA3; PRLTS5; progressive external ophthalmoplegia 1; progressive external ophthalmoplegia 1 (human); progressive external ophthalmoplegia 1 homolog; progressive external ophthalmoplegia 1 protein; Progressive external ophthalmoplegia 1 protein homolog; SANDO; SCA 8; SCA8; T7 gp4-like protein with intramitochondrial nucleoid localization; T7 helicase-related protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; twinkle; Twinkle mtDNA helicase; twinkle protein, mitochondrial; twinkle protein, mitochondrial-like; Twinkle protein, mitochondrial-like protein; Twinl; Twnk; wu:fi04d09
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56652
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96RR1
• Gene Symbols: TWNK
• Immunogen: Recombinant protein corresponding to Human PEO1. Recombinant protein control fragment (Product #RP-102228).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG