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Invitrogen™ PEN2 Polyclonal Antibody

Product Code. 12818442
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12818442 100 μg 100µg
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Product Code. 12818442 Supplier Invitrogen™ Supplier No. PA520302

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Description

Rabbit Polyclonal Antibody

A suggested positive control is A-20 cell lysate. PA5-20302 can be used with blocking peptide PEP-0427.

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PEN2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PSENEN
Gene Accession No. Q6QI68, Q9CQR7, Q9NZ42
Gene Alias 1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037
Gene Symbols PSENEN
Host Species Rabbit
Immunogen A 13 amino acid peptide from near the amino terminus of human PEN2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292788, 55851, 66340
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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