Invitrogen™ PEAR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583262

Product Code. 16310225

Description

Immunogen sequence: PSDPNTCSFW ESFTTTTKES HSRPFSLLPS EPCERPWEGP HTCPQPTVVY RTVYRQVVKT DHRQRLQCCH GFYES Highest antigen sequence indentity to the following orthologs: Mouse - 80%, Rat - 79%.

Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

Specifications

• Antigen: PEAR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEAR1
• Gene Alias: 3110045G13Rik; hPEAR1; Jagged and Delta protein; Jedi; Jedi-1; MEGF12; mPEAR1; Multiple EGF-like domains protein 12; multiple EGF-like-domains 12; multiple epidermal growth factor-like domains protein 12; Pear1; Platelet endothelial aggregation receptor 1; protein Jedi; RGD1305653; RP11-107D16.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 375033
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5VY43
• Gene Symbols: PEAR1
• Immunogen: Recombinant protein corresponding to Human PEAR1. Recombinant protein control fragment (Product #RP-95727).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG