Invitrogen™ PDX1 Recombinant Rabbit Monoclonal Antibody (5H2B1)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557981

Product Code. 30283440

Beschreibung

Immunogen sequence: NLTERHIKIW FQNRRMKWKK EEDKKRGGGT AVGGGGVAEP EQDCAVTSGE ELLALPPPPP PGGAVPPAAP VAAREGRLPP GLSASPQPSS VAPRRPQEPR.

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Spezifikation

• Antigen: PDX1
• Classification: Recombinant Monoclonal
• Concentration: 1.32 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P52946, P52947
• Gene Symbols: PDX1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 184-283 of human PDX1 (NP_000200.1).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5H2B1
• Conjugate: Unconjugated
• Gene: PDX1
• Gene Alias: DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 18609, 29535
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid