Invitrogen™ PDX1 Recombinant Rabbit Monoclonal Antibody (24GB1380)

Rabbit Recombinant Monoclonal Antibody

Marca:  Invitrogen™ MA557534

Código de producto. 30275690

Descripción

PDX1 Recombinant Monoclonal Antibody for Western Blot, Flow

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Especificaciones

• Antigen: PDX1
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: PDX1
• Gene Alias: DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29535, 3651
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB1380
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P52945, P52947
• Gene Symbols: PDX1
• Immunogen: A synthesized peptide derived from human PDX1 (aa 224-283).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG