Invitrogen™ PDSS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558217

Product Code. 15706101

Description

Immunogen sequence: MGKPTSADLK LGLATGPVLF ACQQFPEMNA MIMRRFSLPG DVDRARQYVL QSDGVQQTTY LAQQYCHEAI REISKLRPSP ERDALIQLSE IVLT Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Specifications

• Antigen: PDSS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDSS1
• Gene Alias: 2610203G20Rik; 2700031G06Rik; All-trans-decaprenyl-diphosphate synthase subunit 1; COenzyme Q (ubiquinone) biosynthesis family member (coq-1)-like; coenzyme Q1 homolog; COQ1; COQ10D2; decaprenyl diphdsphate synthase subunit1; decaprenyl diphosphate synthase subunit 1; decaprenyl pyrophosphate synthase subunit 1; decaprenyl pyrophosphate synthetase subunit 1; decaprenyl-diphosphate synthase subunit 1; DPS; Dps1; hDPS1; hypothetical protein LOC550349; LOW QUALITY PROTEIN: decaprenyl-diphosphate synthase subunit 1; mDLP1; MGC70953; mSPS1; PDSS1; polyprenyl pyrophosphate synthetase; prenyl (decaprenyl) diphosphate synthase, subunit 1; prenyl (solanesyl) diphosphate synthase, subunit 1; prenyl diphosphate synthase, subunit 1; RP13-16H11.3; solanesyl-diphosphate synthase subunit 1; SPS; Sps1; subunit 1 of decaprenyl diphosphate synthase; subunit 1 of solanesyl diphosphate synthase; TPRT; TPT; TPT 1; trans-prenyltransferase; trans-prenyltransferase (TPT); trans-prenyltransferase 1; wu:fc11f12; wu:fd05d05; zgc:112058
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23590, 56075
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q33DR2, Q5T2R2
• Gene Symbols: PDSS1
• Immunogen: Recombinant protein corresponding to Human PDSS1. Recombinant protein control fragment (Product #RP-97102).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG