Invitrogen™ PDE4B/PDE4C/PDE4D Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599682

Product Code. 16683925

Description

Antibody detects endogenous levels of total PDE4B/C/D.

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: PDE4B/PDE4C/PDE4D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDE4C
• Gene Alias: 9630011N22Rik; ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D6; cyclic AMP specific phosphodiesterase PDE4D5A; Dpde1; DPDE3; Dpde4; dunce; dunce-like phosphodiesterase E4; E130301F19Rik; HSPDE4D; PDE21; PDE32; PDE43; Pde4b; Pde4c; PDE4D; PDE4DN2; PDEIVB; phosphodiesterase 4B; phosphodiesterase 4B, cAMP specific; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); phosphodiesterase 4C; phosphodiesterase 4C, cAMP specific; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila); phosphodiesterase 4D; phosphodiesterase 4D, cAMP specific; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); phosphodiesterase E1 dunce homolog; R74983; STRK1; testicular tissue protein Li 136
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110385, 18578, 238871, 5142, 5143, 5144
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q01063, Q07343, Q08493, Q08499, Q3UEI1
• Gene Symbols: PDE4B, PDE4C, PDE4D
• Immunogen: A synthesized peptide derived from human PDE4B(Accession Q07343), corresponding to amino acid residues G36-A86.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG